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FeverPAIN score for strep throat

Estimate the chance that a sore throat is caused by group A streptococcus from five simple findings, and see how the score guides antibiotic use.

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FeverPAIN score

3

2 to 3: intermediate; no antibiotic or a delayed prescription

Chance of streptococcus in the derivation study

37%

This calculator is for general information and education. It is not medical advice and does not replace the judgment of a doctor, nurse or pharmacist who knows the full clinical picture.

Most sore throats are caused by viruses and get better on their own within a week. Only about a quarter to a third of adults and children seen for a sore throat have group A streptococcus, the bacterium that antibiotics can treat. The FeverPAIN score was developed in England by Paul Little and colleagues in 2013 to help decide who might benefit from an antibiotic, and it is recommended by NICE in the UK.

The five items

Each item scores 1 point, and the name is a reminder of them:

Letter Item
Fever fever in the last 24 hours
Purulence pus on the tonsils
Attend rapidly symptoms for 3 days or less before the visit
Inflamed tonsils severely inflamed tonsils
No cough or coryza no cough and no runny or blocked nose

Example

A teenager who had a fever last night, has had a sore throat for two days and has no cough or cold scores 3: an intermediate result, with strep found in roughly a third of similar patients.

What the score means

Score Strep in the derivation study Suggested approach
0 to 1 13 to 18% no antibiotic
2 to 3 34 to 40% no antibiotic, or a delayed prescription to use only if things get worse
4 to 5 62 to 65% an immediate antibiotic or a delayed prescription can be considered

In the original trial, using the score cut antibiotic prescribing by about a third while patients felt better slightly faster.

FeverPAIN or Centor?

The Centor score (and the McIsaac version, which adds age) is used more in North America and in France, often together with a rapid strep test in the office. FeverPAIN was designed for primary care where testing is not routine. Both help identify who is unlikely to have strep.

When to seek care quickly

Whatever the score, see a doctor urgently for trouble breathing or swallowing saliva, drooling, a muffled voice, a swelling on one side of the throat, a stiff neck, a rash, or if you feel very unwell. Painkillers such as paracetamol or ibuprofen relieve the pain in all cases.

Frequently asked questions

What does FeverPAIN stand for?

Fever, Purulence, Attend rapidly (within 3 days), Inflamed tonsils and No cough or coryza.

What FeverPAIN score needs antibiotics?

A score of 4 or 5 makes strep likely, and an immediate or delayed antibiotic can be considered.

Is FeverPAIN better than Centor?

Both perform similarly; FeverPAIN was built for primary care without testing, Centor is often paired with a rapid strep test.

Can I use FeverPAIN for children?

It was derived in patients aged 3 and over, so it applies to children from that age.

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Results are estimates provided for information purposes. They do not replace professional advice.