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GRACE risk score (in-hospital death)

Estimate the risk of death in hospital after an acute coronary syndrome from age, heart rate, blood pressure, creatinine, Killip class, cardiac arrest, ST deviation and troponin.

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Results

GRACE score

136

Intermediate risk: in-hospital death 1 to 3%
Age points
58
Heart rate points
9
Blood pressure points
34
Creatinine points
7

This calculator is for general information and education. It is not medical advice and does not replace the judgment of a doctor, nurse or pharmacist who knows the full clinical picture.

The GRACE score comes from the Global Registry of Acute Coronary Events, an international registry of tens of thousands of patients admitted with a heart attack or unstable angina. The in-hospital model published by Granger and colleagues in 2003 uses eight findings available on arrival to estimate the risk of dying before discharge. European guidelines use it to decide how quickly a patient with a non-ST-elevation acute coronary syndrome (NSTE-ACS) should have coronary angiography.

The points

Item Points
Age 0 (under 30) to 100 (90 or older)
Heart rate 0 (under 50) to 46 (200 or more)
Systolic blood pressure 58 (under 80) down to 0 (200 or more)
Creatinine 1 (under 0.4 mg/dL) to 28 (4 mg/dL or more)
Killip class 0, 20, 39 or 59
Cardiac arrest at admission 39
ST-segment deviation 28
Elevated cardiac enzymes 14

Low blood pressure scores more than high blood pressure, because a failing heart cannot keep the pressure up. Age weighs the most: a 75-year-old starts with 75 points before anything else is counted.

Example

A 65-year-old (58 points) with a heart rate of 80 (9), blood pressure of 130 mmHg (34), creatinine of 1.0 mg/dL (7), no heart failure (0) and ST depression on the ECG (28) scores 136: intermediate risk of in-hospital death in NSTE-ACS.

Risk categories

Low Intermediate High
NSTE-ACS 108 or less (under 1%) 109 to 140 (1 to 3%) over 140 (over 3%)
STEMI 125 or less (under 2%) 126 to 154 (2 to 5%) 155 or more (over 5%)

How it guides care

In NSTE-ACS, a GRACE score above 140 is one of the criteria for an early invasive strategy, with angiography within 24 hours. Patients with very high-risk features, such as shock, refractory pain or life-threatening arrhythmias, go to the catheter lab immediately whatever the score.

Limits

The score was built from registry data and estimates average risk; it does not include ejection fraction, bleeding risk or frailty. A second GRACE model estimates death or heart attack at six months. Use this calculator alongside clinical judgment, and weigh bleeding risk with a tool such as CRUSADE.

Frequently asked questions

What is a high GRACE score?

In NSTE-ACS, over 140 means more than 3% risk of in-hospital death and favors angiography within 24 hours.

What does the GRACE score predict?

The in-hospital model used here predicts death before discharge. Another GRACE model predicts death or heart attack at 6 months.

Can I enter creatinine in µmol/L?

This version uses mg/dL. Divide µmol/L by 88.4 to convert.

Does GRACE include bleeding risk?

No. Use CRUSADE alongside it to weigh the bleeding risk.

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Results are estimates provided for information purposes. They do not replace professional advice.