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NEXUS: does this neck injury need imaging?

Check the five NEXUS low-risk criteria after blunt trauma: if none is present, cervical spine imaging can safely be skipped.

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High-risk criteria present

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None present: low risk, imaging is not needed (sensitivity 99.6% in the NEXUS study)

This calculator is for general information and education. It is not medical advice and does not replace the judgment of a doctor, nurse or pharmacist who knows the full clinical picture.

Who needs a neck scan after an injury?

After a car crash, a fall or a sports injury, emergency teams must decide whether to image the cervical spine. Missing a fracture can lead to paralysis, but scanning everyone exposes patients to radiation, costs time and money and fills scanners. The NEXUS study, the National Emergency X-Radiography Utilization Study, followed 34,069 patients at 21 US emergency departments and published a simple rule in 2000.

The five low-risk criteria

Imaging is not needed if the patient has none of the following:

  1. Midline tenderness: pain when pressing on the back of the neck, along the spine.
  2. Intoxication: alcohol or drugs, judged by history or examination.
  3. Altered alertness: a Glasgow score below 15, disorientation, delayed or inappropriate answers.
  4. Focal neurologic deficit: weakness, numbness or tingling in a limb.
  5. Painful distracting injury: one severe enough to mask neck pain, such as a long-bone fracture, a large laceration, a burn or a crush injury.

If any is present, cervical spine imaging is indicated. In adults, CT is now preferred to plain X-rays.

Accuracy

In the original study, 818 patients had a cervical spine injury, 578 of them clinically significant. The rule flagged 576 of those 578, a sensitivity of 99.6%, and would have avoided imaging in 12.6% of patients. Its specificity is low, about 13%, which is expected for a rule designed never to miss an injury.

Worked example

A 34-year-old cyclist is brought in after a fall. He is fully alert and sober, says his neck feels stiff but has no pain when the midline is pressed, moves all limbs normally and has only abrasions on his arm. None of the five criteria is present, so no imaging is needed. If he had a painful wrist fracture, that would count as a distracting injury, and imaging would be indicated.

NEXUS and the Canadian C-spine rule

The Canadian C-spine rule, published in 2001, adds high-risk factors (age 65 or more, a dangerous mechanism, numbness in the limbs) and a test of active neck rotation. In a 2003 comparison it was more sensitive and more specific than NEXUS, but it only applies to alert, stable adults. Many emergency departments use either rule; both are much safer than imaging on instinct.

Limits

NEXUS applies only to blunt trauma, not penetrating injuries. In older adults, whose fractures can occur with little force, many clinicians have a lower threshold for imaging. Whatever the score, persistent pain or new symptoms should prompt reassessment.

Frequently asked questions

What are the NEXUS criteria?

Five clinical criteria from the National Emergency X-Radiography Utilization Study, published by Jerome Hoffman and colleagues in 2000. If an alert, sober patient has none of them after blunt trauma, cervical spine imaging is not needed.

How accurate is NEXUS?

In the original study of 34,069 patients, the rule had a sensitivity of 99.6% for clinically significant cervical spine injury. It allowed imaging to be skipped in about 12.6% of patients.

NEXUS or the Canadian C-spine rule?

Both are validated. The Canadian rule was more sensitive and specific in a head-to-head study, but it only applies to alert, stable adults and has more steps. NEXUS is simpler and has also been used in children.

What counts as a distracting injury?

A painful injury that could keep the patient from noticing neck pain, such as a long-bone fracture, a large laceration, a burn, a crush injury or a visceral injury. Clinical judgment decides what is distracting.

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Results are estimates provided for information purposes. They do not replace professional advice.