This calculator is for general information and education. It is not medical advice and does not replace the judgment of a doctor, nurse or pharmacist who knows the full clinical picture.
What SCORE2 is
SCORE2 is the cardiovascular risk model of the European Society of Cardiology, introduced in its 2021 prevention guidelines. It estimates the 10-year risk of a fatal or non-fatal cardiovascular event, meaning heart attack, stroke or cardiovascular death, in people aged 40 to 69 who do not already have cardiovascular disease. It replaced the older SCORE chart, which only counted deaths.
The model was developed from about 45 cohorts with close to 700,000 participants, then recalibrated to four groups of countries using national rates of cardiovascular disease.
Inputs
- Age and sex
- Current smoking
- Systolic blood pressure
- Total and HDL cholesterol (the charts show non-HDL cholesterol, which is total minus HDL)
- The risk region of the country where you live
Risk regions
| Region | Examples |
|---|---|
| Low | France, Spain, Belgium, the Netherlands, the UK |
| Moderate | Germany, Italy, Sweden, Portugal |
| High | Poland, Hungary, Czechia, Turkey |
| Very high | Romania, Ukraine, Bulgaria, Egypt |
SCORE2 is not calibrated for the United States, where doctors use the Pooled Cohort Equations or PREVENT.
Thresholds by age
| Age | Low to moderate | High | Very high |
|---|---|---|---|
| Under 50 | under 2.5% | 2.5% to 7.4% | 7.5% or more |
| 50 to 69 | under 5% | 5% to 9.9% | 10% or more |
At high risk, treating risk factors such as blood pressure and cholesterol should be considered; at very high risk it is recommended. The thresholds are lower in younger people because a modest 10-year risk adds up to a large lifetime risk.
How the calculation works
Each factor is centered (age around 60, systolic pressure around 120 mmHg, total cholesterol around 6 mmol/L, HDL around 1.3 mmol/L) and weighted, with age interactions, to give an uncalibrated risk. That risk is then converted to the chosen region with two scaling factors. A 55-year-old non-smoking man in a low-risk country with a systolic of 140 mmHg, total cholesterol of 213 mg/dL (5.5 mmol/L) and HDL of 50 mg/dL has a risk of about 4.5%.
Related tools
SCORE2-OP covers people aged 70 and over, and SCORE2-Diabetes, published in 2023, covers people with type 2 diabetes. People with kidney disease, familial hypercholesterolemia or established disease are assessed differently.