Why sodium needs correcting
When blood sugar is very high, as in diabetic ketoacidosis or the hyperosmolar hyperglycemic state, glucose pulls water out of cells into the bloodstream. That extra water dilutes sodium, so the lab result looks lower than the body’s true water balance. As insulin brings glucose down, water moves back into cells and sodium rises.
The corrected sodium predicts where sodium will land once glucose is normal. It helps choose fluids and spot hidden dehydration.
The two formulas
With glucose in mg/dL:
- Katz (1973): corrected Na = Na + 1.6 × (glucose − 100) ÷ 100
- Hillier (1999): corrected Na = Na + 2.4 × (glucose − 100) ÷ 100
Katz derived his factor from theory. Hillier measured it in healthy volunteers given a glucose load and found 2.4 fits better, especially above about 400 mg/dL. Many references show both.
Worked example
Measured sodium 130 mmol/L, glucose 600 mg/dL:
- Glucose above the reference: 600 − 100 = 500 mg/dL.
- Katz: 130 + 1.6 × 5 = 138.0 mmol/L.
- Hillier: 130 + 2.4 × 5 = 142.0 mmol/L.
A sodium that looked low is in fact normal or slightly high once corrected. The patient is not truly hyponatremic and may be short of free water.
Reading the result
| Corrected sodium | Meaning |
|---|---|
| below 135 | true hyponatremia |
| 135 to 145 | normal range |
| above 145 | hypernatremia, free water deficit likely |
If the corrected value is high, see the free water deficit calculator to estimate how much water is missing.
Units
Glucose in mmol/L is multiplied by 18 to get mg/dL: 33.3 mmol/L equals 600 mg/dL. The calculator’s unit selector does this for you.
Limits
The correction assumes glucose is the only extra solute. Mannitol, contrast dye or very high lipids or proteins (pseudohyponatremia with some lab methods) can also affect the result. Sodium should be checked often during treatment instead of relying on a single prediction.
This calculator is for general information and education. It is not medical advice and does not replace the judgment of a doctor, nurse or pharmacist who knows the full clinical picture.